It’s been a record year! 2016 – A year in retrospect.

Although data will still be coming in over the next few months we have made a step farther both quality- and quantity-wise.

Wh have reached a record number of publications for the Turel group this year with a full dozen of new scientific papers in reputable journals such as Journal of Inorganic Biochemistry, Dalton Transactions, Journal of Computational Chemistry and RSC Advances. As of April 4th we have also reported a record yearly number of citations (423).

Here are the highlights of 2016:

  • 12 scientific papers,
  • 1 book chapter (still upcoming, the same one as in 2015 it has fallen into a publishing limbo),
  • 9 conference abstracts/posters,
  • 4 invited lectures (Iztok Turel: 53rd Meeting of the Serbian chemical society, University of Kragujevac, Serbia; 3rd International symposium on functional metal complexes that bind to biomolecules, Mallorca, Spain; 3rd International conference on herbal and synthetic drug studies, Pune, India, Jakob Kljun: 53rd Meeting of the Serbian chemical society, University of Kragujevac, Serbia),
  • 4 BSc theses (Primož Tič, Nina Podjed, Simona Gričar, Tomaž Zornik), 2 MSc theses (Veronika Rovanšek, Monika Uzelac), 1 PhD thesis (dr. Sara Seršen),
  • Dr. Iztok Turel was awarded the Zois certificate of recognition for important achievements in the field of chemistry. It is one of the Highest State Awards in the Field of Scientific-Research and Science Development Activities (Zois awards and recognitions, the Ambassador of Science Awards of the Republic of Slovenia and Puh awards). The Ph.D. thesis of our former member dr. Sara Seršen was awarded a prize by Krka Pharmaceutical Factory (Novo mesto, Slovenia) for special research achievements.

We are also at a record-high number of group members with the appointment of researcher Jakob Kljun to a permanent position of assistant/researcher (80/20), 1 guest post-doc researcher from Belgrade, Serbia, 3 PhD students, 4 MSc students, 1 Erasmus BSc student from Lisbon, Portugal and another 2 Slovenian BSc students totalling 13 group members.

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Ru-team 2017 under blossoming Japanese cherry trees in front of the FKKT building

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Number of publications

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Number of citations

EurJIC’s Cluster Issue on Metal Anticancer Complexes with our Microreview

We are pleased to announce that EurJIC’s Cluster Issue on “Metal Anticancer Complexes – Activity, Mechanism of Action and Future Perspectives” issue 12/2017, has just gone online! Guest edited by Professors Enzo Alessio and Zijian Guo, the cluster issue provides readers with a great collection of papers highlighting the stimulating developments in the field of metal anticancer complexes.

http://onlinelibrary.wiley.com/doi/10.1002/ejic.v2017.12/issuetoc

Our contribution to this special issue is a microreview entitled:

‘β-Diketones as scaffolds for anticancer drug design. From organic building blocks to natural products and metallodrug components.’

Check it out at: http://onlinelibrary.wiley.com/doi/10.1002/ejic.201601314/full

Awards and recognitions of group members

The Ph.D. thesis of our ex-member dr. Sara Seršen was awarded by Krka Pharmaceutical Factory (Novo mesto, Slovenia) for special research achievements. See more details at:

https://www.krkinenagrade.si/sl/o-krkinih-nagradah

The Highest State Awards in the Field of Scientific-Research and Science Development Activities (Zois awards and recognitions, the Ambassador of Science Awards of the Republic of Slovenia and Puh awards) were given out during a formal ceremony at Cankarjev dom in Ljubljana on 21st of November 2016. Prof. Dr. Iztok Turel was awarded the Zois certificate of recognition for important achievements in the field of chemistry. See names of other prize winners and other details at:

http://www.mizs.gov.si/si/medijsko_sredisce/novica/browse/2/article/62/9845/

New members of the group

Postdoc Božidar Čobeljić is permanently employed as assistant at University of Belgrade, Serbia. He started his one-year stay in October 2016. His main field of research are metal complexes of Schiff bases of 2-quinolinecarboxaldehyde, 3-acetylpyridine and 2-(diphenylphosphino)benzaldehyde. During his stay he is planning the synthesis and characterization of new hydrazide ligands and their d- metal complexes.

New PhD student (young researcher) Jerneja Kladnik has started her doctoral studies in October 2016. Her study is funded by ARRS (Slovenian Research Agency) for four years. Before joining our group, Jerneja has finished a MSc in Pharmacy at the Faculty of Pharmacy in Ljubljana.

Catarina Cardoso Páscoa (4th year BSc student, Chemistry program @ Universidade Nova de Lisboa, Portugal) joined us for one term of Erasmus practical training. At the Turel group she is involved in synthetic ruthenium chemistry on the subject of pyrithione metal complexes.

The Turel group welcomes our new team members and hopes for their pleasant and productive stay.

New article in Dalton Transactions with Dean’s award

Check out the newest accepted publication of Turel group in Dalton Transactions in collaboration with our colleagues from the Faculty of Pharmacy:

Clioquinol-ruthenium complex impairs tumour cell invasion by inhibiting cathepsin B activity

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First author Ana Mitrović has been awarded the Dean’s award for most notable scientific achievements in 2016 at the Faculty of Pharmacy of the University of Ljubljana for the research presented in this scientific paper. Congratulations!

Visit by prof. Peter J. Sadler

Professor Peter J. Sadler from the University of Warwick, UK has visited our labs in mid-April and held a lecture fot the students of the FKKT doctoral study programme ‘Chemical Sciences’ entitled ‘The Elements od Life and Medicine’. The national newspaper Delo has in this occasion published an interview with prof. Sadler. You can read it (in Slovenian) here.

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Special issue of JIB in occasion of COST CM1105 meeting

The Journal of Inorganic Biochemistry is dedicating its 160th volume (July 2016) to the COST CM1105 action ‘Functional metal complexes that bind to biomolecules’. Within this issue you can find two contribitions of the Turel research group. The first contrubution is entitled ‘Interactions of two cytotoxic organoruthenium(II) complexes with G-quadruplex’ by our former team member Sara Seršen in collaboration with the research team of prof. Janez Plavec from the National institute of Chemistry, Ljubljana, Slovenia. The second paper, entitled ‘Cobalt(II) complexes with non-steroidal anti-inflammatory drugs and α-diimines’ continues our successful partnership with prof. George Psomas in the field of structural determination and biological evaluation of 3d transition metal complexes of clinical agents.

Article in Dalton Transactions

Check out our latest research published in Dalton Transactions.

‘Pyrithione-based ruthenium complexes as inhibitors of aldo–keto reductase 1C enzymes and anticancer agents’

Congratulations to Sara Seršen on her PhD

The Turel group congratulates Srara Seršen on her successful defence of her PhD thesis with the title “Synthesis of novel ruthenium complexes with possible biological and catalytic properties“. We wish her all the best and continued success at her new job.

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Off to a new adventure!

After a brief return following her parental leave Sara Seršen has moved on to a new challenge. As of April 1st she is starting her new job in the pharmaceutical industry at ‘Lek d.d., a Sandoz company’. We wish her all the best and look forward to her PhD defense on April 25th.

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From left to right: Matija Uršič, Tanja Lipec, Sara Seršen, Iztok Turel, Jakob Kljun, Špela Peršič